Titanium dioxide R-5566 can be widely used in indoor and outdoor coatings, latex paints, powder coatings, inks, papermaking, rubber, plastics, masterbatches.

The lack of clear regulations and controls explains that P25TiO₂NPs are still found in many of the commercialized sunscreens in the market. Some of them are coated to reduce the photoactivity of the anatase form, which is known to be responsible for tissue damage, but not enough studies were made on these coated forms. The anatase photoactivity could trigger the production of reactive oxygen species (ROS) generation, as it was stated before. The ROS are chemically reactive species containing oxygen, such as peroxides, superoxide, hydroxyl radical, and singlet oxygen. They are regularly produced in the biological milieu and counterbalanced by physiological antioxidant defense mechanisms. However, an abrupt increase of ROS may result in non-reversible damage to the skin cells. The effects of coated and uncoated P25TiO₂NPs need therefore to be studied, and articles on this topic present different conclusions. [11], [12], [13] Recent literature on this topic found that TiO₂NPs inhalation provokes serious genotoxicity and DNA damage [14], [15], [16], [17]. On the other hand, some studies in rats have reported no significant harm to genetic material [18], [19], [20], [21], [22].

Overall, CAS 13463-67-7 stands out as a reliable and trustworthy titanium dioxide factory that is committed to delivering top-quality products and services. With its focus on quality, sustainability, and innovation, the factory has established itself as a leader in the industry and a preferred partner for companies looking to source titanium dioxide for their dyes and pigments.

The most common foods containing titanium dioxide are chewing gum, candies, pastries, chocolates, coffee creamers, and cake decorations (1Trusted Source, 3Trusted Source).

Are there any other products where you use titanium dioxide?

Titanium dioxide (TiO₂) is by far the most suited white pigment to obtain whiteness and hiding power in coatings, inks and plastics. This is because it has an extremely high refractive index and it does not absorb visible light. TiO₂ is also readily available as particles with the right size (d ≈ 280 nm) and the right shape (more or less spherical) as well as with a variety of post-treatments.

However, the pigment is expensive, especially when the volume prices of systems are used. And, there always remains a need to develop a full-proof strategy to obtain the best results in terms of cost/performance ratio, scattering efficiency, dispersion… while using it in coating formulations. Are you searching for the same?

Explore the detailed knowledge of TiO₂ pigment, its scattering efficiency, optimization, selection, etc. to achieve the best possible white color strength and hiding power in your formulations.

Macromolecular oxidation was detected in proteins by the colorimetric measurement of Advanced Oxidation Protein Products (AOPP) and in lipids by the colorimetric quantification of malondialdehyde (MDA). Standard curves were run with chloramine-T and 1,1,3,3 tetraethoxypropane (TEP) for AOPP and MDA methods, respectively [29], [30], [31]. Values were normalized to initial protein content in samples, measured with Bradford reagent [32]. The standard deviation of at least six measures was calculated and p-value < 0.05 were considered significant.

There is some concern regarding skin and intestinal absorption of titanium dioxide nanoparticles, which are less than 100 nm in diameter.

ROS were detected through the colorimetric assay employing the nitro-blue tetrazolium salt (NBT salt) by reading the absorbance of the reduced blue molecule.